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1

The innate immune system in chronic cardiomyopathy: a European Society of Cardiology (ESC) scientific statement from the Working Group on Myocardial Function of the ESC

Frantz, Stefan, Falcao-Pires, Ines, Balligand, Jean-Luc, Bauersachs, Johann, Brutsaert, Dirk, Ciccarelli, Michele, Dawson, Dana, de Windt, Leon J., Giacca, Mauro, Hamdani, Nazha, Hilfiker-Kleiner, Den

Journal:

European Journal of Heart Failure

Year:

2018

Language:

english

File:

PDF, 3.71 MB

english, 2018

2

Association of Vitamin B12 Deficiency with Fatigue and Depression after Lacunar Stroke

Huijts, Marjolein, Duits, Annelien, Staals, Julie, van Oostenbrugge, Robert J., de Windt, Leon J.

Journal:

Year:

2012

Language:

english

File:

PDF, 57 KB

english, 2012

3

Heart spotting

Hamid el Azzouzi, Leon J. De Windt

Journal:

Basic Research in Cardiology

Year:

2008

Language:

english

File:

PDF, 158 KB

english, 2008

4

Phospholipase A2-mediated hydrolysis of cardiac phospholipids: The use of molecular and transgenic techniques

Leon J. De Windt, Robert S. Reneman, Ger J. Van der Vusse, Marc Van Bilsen

Journal:

Molecular and Cellular Biochemistry

Year:

1998

Language:

english

File:

PDF, 212 KB

english, 1998

5

Fibroblast growth factor-1 improves cardiac functional recovery and enhances cell survival after ischemia and reperfusion: A fibroblast growth factor receptor, protein kinase c, and tyrosine kinase-dependent mechanism

Meindert Palmen, Mat J.A.P. Daemen, Leon J. De Windt, Jodil Willems, Willem R.M. Dassen, Sylvia Heeneman, Rene Zimmermann, Marc Van Bilsen, Pieter A. Doevendans

Journal:

Journal of the American College of Cardiology

Year:

2004

Language:

english

File:

PDF, 656 KB

english, 2004

6

MicroRNAs as Biomarkers for Myocardial Infarction

Kanita Salic, Leon J. De Windt

Journal:

Current Atherosclerosis Reports

Year:

2012

Language:

english

File:

PDF, 192 KB

english, 2012

7

Low-Dose FK506 Blocks Collar-Induced Atherosclerotic Plaque Development and Stabilizes Plaques in ApoE−/− Mice

Marjo M. P. C. Donners, Ilze Bot, Leon J. De Windt, Theo J. C. Van Berkel, Mat J. A. P. Daemen, Erik A. L. Biessen, Sylvia Heeneman

Journal:

American Journal of Transplantation

Year:

2005

Language:

english

File:

PDF, 389 KB

english, 2005

8

Cloning and Cellular Distribution of a Group II Phospholipase A2Expressed in the Heart

Leon J. De Windt, Peter H.M. Willemsen, Stephanie Pöpping, Ger J. Van der Vusse, Robert S. Reneman, Marc Van Bilsen

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1997

Language:

english

File:

PDF, 1.40 MB

english, 1997

9

Reversal of Cardiac Hypertrophy in Transgenic Disease Models by Calcineurin Inhibition

Hae W Lim, Leon J De Windt, Janice Mante, Thomas R Kimball, Sandra A Witt, Mark A Sussman, Jeffery D Molkentin

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2000

Language:

english

File:

PDF, 1.24 MB

english, 2000

10

In calcineurin-induced cardiac hypertrophy expression of Nav1.5, Cx40 and Cx43 is reduced by different mechanisms

Marti F.A. Bierhuizen, Mohamed Boulaksil, Leonie van Stuijvenberg, Roel van der Nagel, Anita T. Jansen, Nancy A.M. Mutsaers, Cansu Yildirim, Toon A.B. van Veen, Leon J. de Windt, Marc A. Vos, Harold V

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2008

Language:

english

File:

PDF, 1.74 MB

english, 2008

11

Quaero muneris: Exploring microRNA function in cardiovascular disease

Virginie Kinet, Ellen Dirkx, Leon J. De Windt

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2012

Language:

english

File:

PDF, 125 KB

english, 2012

12

Small changes can make a big difference — MicroRNA regulation of cardiac hypertrophy

Monika M. Gladka, Paula A. da Costa Martins, Leon J. De Windt

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2012

Language:

english

File:

PDF, 550 KB

english, 2012

13

Characterization of protein kinase C (PKC) function in cardiomyocyte hypertrophy

Julian C. Braz, Leon J. De Windt, Jeffery D. Molkentin

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2001

Language:

english

File:

PDF, 149 KB

english, 2001

14

Unraveling the significance of the hypertrophic calcineurin-NFAT pathway by viral mediated inhibition of its components

Eva van Reeij, Chiel C. de Theije, Jeffrey D. Melkentin, Pieter A. Doevendans, Leon J. de Windt

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2001

Language:

english

File:

PDF, 138 KB

english, 2001

15

Molecular Basis of Cardiovascular Disease || Generation and Cloning of Genetically Modified Animals

De Windt, Leon J.

Year:

1999

Language:

english

File:

PDF, 41 KB

english, 1999

16

Resveratrol Improves Survival, Hemodynamics and Energetics in a Rat Model of Hypertension Leading to Heart Failure

Rimbaud, Stéphanie, Ruiz, Matthieu, Piquereau, Jérôme, Mateo, Philippe, Fortin, Dominique, Veksler, Vladimir, Garnier, Anne, Ventura-Clapier, Renée, de Windt, Leon J.

Journal:

Year:

2011

Language:

english

File:

PDF, 865 KB

english, 2011

17

Regulation of fetal gene expression in heart failure

Dirkx, Ellen, da Costa Martins, Paula A., De Windt, Leon J.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2013

Language:

english

File:

PDF, 775 KB

english, 2013

18

Towards modern genetics, diagnostics and therapeutics of heart failure in a new era

De Windt, Leon J., Doevendans, Pieter A.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2013

Language:

english

File:

PDF, 178 KB

english, 2013

19

Discrepancy Between Acute and Long-Term Effects of the Calmodulin-Camkii-Calcineurin Pathway on Arrhythmogenesis in the CAVB Dog

Bourgonje, Vincent J.A., Schoenmakers, Marieke, Beekman, Jet D.M., van der Nagel, Roel, de Windt, Leon J., van Veen, Toon A.B., Vos, Marc A.

Journal:

Year:

2009

Language:

english

File:

PDF, 104 KB

english, 2009

20

Relevance of calmodulin/CaMKII activation for arrhythmogenesis in the AV block dog

Schoenmakers, Marieke, Bourgonje, Vincent J.A., Beekman, Jet D.M., van der Nagel, Roel, Houtman, Marien J.C., Miedema, Lars F., Antoons, Gudrun, Sipido, Karin, de Windt, Leon J., van Veen, Toon A.B.

Journal:

Year:

2012

Language:

english

File:

PDF, 2.28 MB

english, 2012

21

PKCα Regulates the Hypertrophic Growth of Cardiomyocytes through Extracellular Signal-Regulated Kinase1/2 (ERK1/2)

Julian C. Braz, Orlando F. Bueno, Leon J. De Windt and Jeffery D. Molkentin

Journal:

The Journal of Cell Biology

Year:

2002

Language:

english

File:

PDF, 3.89 MB

english, 2002

22

Differential responses of the right ventricle to abnormal loading conditions in mice: pressure vs. volume load

Bartelds, Beatrijs, Borgdorff, Marinus A., Smit-van Oosten, Annemiek, Takens, Janny, Boersma, Bibiche, Nederhoff, Marcel G., Elzenga, Nynke J., van Gilst, Wiek H., De Windt, Leon J., Berger, Rolf M.F.

Journal:

European Journal of Heart Failure

Year:

2011

Language:

english

File:

PDF, 305 KB

english, 2011

23

Targeting myocardial remodelling to develop novel therapies for heart failure

Tarone, Guido, Balligand, Jean-Luc, Bauersachs, Johann, Clerk, Angela, De Windt, Leon, Heymans, Stephane, Hilfiker-Kleiner, Denise, Hirsch, Emilio, Iaccarino, Guido, Knöll, Ralph, Leite-Moreira, Adeli

Journal:

European Journal of Heart Failure

Year:

2014

Language:

english

File:

PDF, 857 KB

english, 2014

24

ESC Working Group on Myocardial Function Position Paper: how to study the right ventricle in experimental models

Leite-Moreira, Adelino F., Lourenço, André P., Balligand, Jean-Luc, Bauersachs, Johann, Clerk, Angela, De Windt, Leon J., Heymans, Stephane, Hilfiker-Kleiner, Denise, Hirsch, Emilio, Iaccarino, Guido,

Journal:

European Journal of Heart Failure

Year:

2014

Language:

english

File:

PDF, 339 KB

english, 2014

25

Lack of UCP3 does not affect skeletal muscle mitochondrial function under lipid-challenged conditions, but leads to sudden cardiac death

Nabben, Miranda, van Bree, Bianca W. J., Lenaers, Ellen, Hoeks, Joris, Hesselink, Matthijs K. C., Schaart, Gert, Gijbels, Marion J. J., Glatz, Jan F. C., da Silva, Gustavo J. J., de Windt, Leon J., Ti

Journal:

Basic Research in Cardiology

Year:

2014

Language:

english

File:

PDF, 1.78 MB

english, 2014

26

NFATc2 Is a Necessary Mediator of Calcineurin-dependent Cardiac Hypertrophy and Heart Failure

Bourajjaj, Meriem, Armand, Anne-Sophie, da Costa Martins, Paula A., Weijts, Bart, van der Nagel, Roel, Heeneman, Sylvia, Wehrens, Xander H., De Windt, Leon J.

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 1.12 MB

english, 2008

27

Non-coding RNA in control of gene regulatory programs in cardiac development and disease

Philippen, Leonne E., Dirkx, Ellen, da Costa-Martins, Paula A., De Windt, Leon J.

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2015

Language:

english

File:

PDF, 326 KB

english, 2015

28

Metabonomic Profiles Delineate the Effect of Traditional Chinese Medicine Sini Decoction on Myocardial Infarction in Rats

Tan, Guangguo, Liao, Wenting, Dong, Xin, Yang, Genjing, Zhu, Zhenyu, Li, Wuhong, Chai, Yifeng, Lou, Ziyang, de Windt, Leon J.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.45 MB

english, 2012

29

Targeting microRNAs in heart failure

Duygu, Burcu, de Windt, Leon J., da Costa Martins, Paula A.

Journal:

Trends in Cardiovascular Medicine

Year:

2015

Language:

english

File:

PDF, 5.60 MB

english, 2015

30

A Deep Sequencing Approach to Uncover the miRNOME in the Human Heart

Leptidis, Stefanos, el Azzouzi, Hamid, Lok, Sjoukje I., de Weger, Roel, Olieslagers, Serv, Kisters, Natasja, Silva, Gustavo J., Heymans, Stephane, Cuppen, Edwin, Berezikov, Eugene, De Windt, Leon J.,

Journal:

Year:

2013

Language:

english

File:

PDF, 867 KB

english, 2013

31

MEF2 transcriptional activity maintains mitochondrial adaptation in cardiac pressure overload

el Azzouzi, Hamid, van Oort, Ralph J., van der Nagel, Roel, Sluiter, Wim, Bergmann, Martin W., De Windt, Leon J.

Journal:

European Journal of Heart Failure

Year:

2010

Language:

english

File:

PDF, 476 KB

english, 2010

32

HypoxamiRs: regulators of cardiac hypoxia and energy metabolism

Azzouzi, Hamid el, Leptidis, Stefanos, Doevendans, Pieter A., De Windt, Leon J.

Journal:

Trends in Endocrinology & Metabolism

Year:

2015

Language:

english

File:

PDF, 609 KB

english, 2015

33

Antisense MicroRNA Therapeutics in Cardiovascular Disease: Quo Vadis?

Philippen, Leonne E., Dirkx, Ellen, Wit, Jan B. M., Burggraaf, J., de Windt, Leon J., da Costa Martins, P. A.

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 1.31 MB

english, 2015

34

Longing for Naiades in Heart Failure∗

Calore, Martina, De Windt, Leon J.

Journal:

Journal of the American College of Cardiology

Year:

2015

Language:

english

File:

PDF, 123 KB

english, 2015

35

Genetics meets epigenetics: Genetic variants that modulate noncoding RNA in cardiovascular diseases

Calore, Martina, De Windt, Leon J., Rampazzo, Alessandra

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2015

Language:

english

File:

PDF, 723 KB

english, 2015

36

State-of-the-art on non-coding RNA bioinformatics, diagnostics and therapeutics in cardiovascular diseases

De Windt, Leon J., Thum, Thomas

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2015

Language:

english

File:

PDF, 162 KB

english, 2015

37

MicroRNAs in heart failure: from biomarker to target for therapy

Vegter, Eline L., van der Meer, Peter, de Windt, Leon J., Pinto, Yigal M., Voors, Adriaan A.

Journal:

European Journal of Heart Failure

Year:

2016

Language:

english

File:

PDF, 1.29 MB

english, 2016

38

Preclinical Development of a MicroRNA-Based Therapy for Elderly Patients With Myocardial Infarction

Gupta, Shashi Kumar, Foinquinos, Ariana, Thum, Sabrina, Remke, Janet, Zimmer, Karina, Bauters, Christophe, de Groote, Pascal, Boon, Reinier A., de Windt, Leon J., Preissl, Sebastian, Hein, Lutz, Batka

Journal:

Journal of the American College of Cardiology

Year:

2016

Language:

english

File:

PDF, 2.97 MB

english, 2016

39

Cardiovascular extracellular microRNAs: emerging diagnostic markers and mechanisms of cell-to-cell RNA communication

Kinet, Virginie, Halkein, Julie, Dirkx, Ellen, Windt, Leon J. De

Journal:

Frontiers in Genetics

Year:

2013

Language:

english

File:

PDF, 555 KB

english, 2013

40

miR-199b-5p is a regulator of left ventricular remodeling following myocardial infarction

Duygu, Burcu, Poels, Ella M., Juni, Rio, Bitsch, Nicole, Ottaviani, Lara, Olieslagers, Servé, de Windt, Leon J., da Costa Martins, Paula A.

Journal:

Non-coding RNA Research

Year:

2017

Language:

english

File:

PDF, 1.67 MB

english, 2017

41

Epigenomic and transcriptomic approaches in the post-genomic era: path to novel targets for diagnosis and therapy of the ischemic heart?

Perrino, Cinzia, Barabási, Albert-Laszló, Condorelli, Gianluigi, Davidson, Sean M., De Windt, Leon, Dimmeler, Stefanie, Engel, Felix B., Hausenloy, Derek J., Hill, Joseph A., Van Laake, Linda W., Leco

Journal:

Cardiovascular Research

Year:

2017

Language:

english

File:

PDF, 435 KB

english, 2017

42

Cardiac remodelling and preeclampsia: an overview of overlapping circulating miRNAs

Mohseni, Zenab, Spaanderman, Marc E.A., Oben, Jolien, Calore, Martina, Derksen, Elianne, Al-Nasiry, Salwan, de Windt, Leon, Ghossein-Doha, Chahinda

Journal:

Ultrasound in Obstetrics & Gynecology

Year:

2017

Language:

english

File:

PDF, 1.43 MB

english, 2017

43

Why Publish in the American Journal of Physiology-Heart and Circulatory Physiology?

Zucker, Irving H., Lindsey, Merry L., Delmar, Mario, De Windt, Leon J., Des Rosiers, Christine, Diz, Debra I., Hester, Robert L., Jones, Steven P., Kanagy, Nancy L., Kitakaze, Masafumi, Liao, Ronglih,

Journal:

American Journal of Physiology - Heart and Circulatory Physiology

Year:

2017

Language:

english

File:

PDF, 309 KB

english, 2017

44

An unbiased silencing screen in muscle cells identifies miR-320a, miR-150, miR-196b, and miR-34c as regulators of skeletal muscle mitochondrial metabolism

Dahlmans, Dennis, Houzelle, Alexandre, Andreux, Pénélope, Jörgensen, Johanna A., Wang, Xu, de Windt, Leon J., Schrauwen, Patrick, Auwerx, Johan, Hoeks, Joris

Journal:

Molecular Metabolism

Year:

2017

Language:

english

File:

PDF, 2.59 MB

english, 2017

45

An integrative translational approach to study heart failure with preserved ejection fraction: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology

Lourenço, Andre P., Leite-Moreira, Adelino F., Balligand, Jean-Luc, Bauersachs, Johann, Dawson, Dana, de Boer, Rudolf A., de Windt, Leon J., Falcão-Pires, Inês, Fontes-Carvalho, Ricardo, Franz, Stefan

Journal:

European Journal of Heart Failure

Year:

2017

Language:

english

File:

PDF, 533 KB

english, 2017

46

MicroRNA-221/222 Family Counteracts Myocardial Fibrosis in Pressure Overload–Induced Heart Failure

Verjans, Robin, Peters, Tim, Beaumont, Francisco Javier, van Leeuwen, Rick, van Herwaarden, Tessa, Verhesen, Wouter, Munts, Chantal, Bijnen, Mitchell, Henkens, Michiel, Diez, Javier, de Windt, Leon J.

Journal:

Year:

2017

Language:

english

File:

PDF, 2.09 MB

english, 2017

47

miR-223: sailing to terra incognita for microRNAs in platelets

Halkein, Julie, De Windt, Leon J.

Journal:

Thrombosis and Haemostasis

Year:

2013

Language:

english

File:

PDF, 69 KB

english, 2013

48

The Complex Exogenous RNA Spectra in Human Plasma: An Interface with Human Gut Biota?

Wang, Kai, Li, Hong, Yuan, Yue, Etheridge, Alton, Zhou, Yong, Huang, David, Wilmes, Paul, Galas, David, de Windt, Leon J.

Journal:

Year:

2012

Language:

english

File:

PDF, 745 KB

english, 2012

49

Characterization of microRNAs Identified in a Table Grapevine Cultivar with Validation of Computationally Predicted Grapevine miRNAs by miR-RACE

Wang, Chen, Shangguan, Lingfei, Kibet, Korir Nicholas, Wang, Xicheng, Han, Jian, Song, Changnian, Fang, Jinggui, de Windt, Leon J.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.41 MB

english, 2011

50

Targeted Gene-Silencing Reveals the Functional Significance of Myocardin Signaling in the Failing Heart

Torrado, Mario, Iglesias, Raquel, Centeno, Alberto, López, Eduardo, Mikhailov, Alexander T., de Windt, Leon J.

Journal:

Year:

2011

Language:

english

File:

PDF, 979 KB

english, 2011

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